Growth Hormone Releasing Hormone Receptor (GHRHR) Antibody (HRP)
169€ (20 µg)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Growth Hormone Releasing Hormone Receptor (GHRHR) Antibody (HRP)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx335886
Tested Applications
ELISA
Description
GHRHR Antibody (HRP) is a Rabbit Polyclonal against GHRHR.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Growth Hormone Releasing Hormone Receptor (GHRHR) Immunogen: Recombinant Human Growth hormone-releasing hormone receptor protein (23-127AA). |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | HRP |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q02643 |
| Gene ID | 2692 |
| Alias | GHRHR,GRF receptor,GRFR,growth hormone-releasing factor receptor,Ghrfr,IGHD4,IGHD1B |
| Background | Antibody anti-GHRHR |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
GHRHR is a G protein-coupled receptor that binds growth hormone-releasing hormone (GHRH), regulating the synthesis and secretion of growth hormone (GH) from the anterior pituitary gland. GHRHR is primarily expressed in pituitary somatotroph cells, where its activation stimulates the cAMP/PKA and MAPK signaling pathways, leading to GH gene transcription and release. Growth hormone plays a critical role in growth, metabolism, and tissue repair by promoting the production of insulin-like growth factor-1 (IGF-1) in peripheral tissues. Mutations or dysregulation of GHRHR are associated with growth hormone deficiencies, leading to short stature, delayed growth, and metabolic imbalances. GHRHR has also been implicated in aging, where reduced GH signaling contributes to age-related declines in muscle mass and bone density. Therapeutically, GHRHR agonists are used to stimulate growth hormone production in patients with GH deficiency, while antagonists are being explored for treating acromegaly and certain cancers where GH overproduction contributes to tumor growth. GHRHR is a key target for modulating growth hormone signaling and managing growth and metabolic disorders.
Productos relacionados
Growth Hormone Releasing Hormone Receptor (GHRHR) Antibody
GHRHR Antibody is a Rabbit Polyclonal Antibody against GHRHR.…
Ver producto
Growth Hormone Releasing Hormone Receptor (GHRHR) Antibody
Rabbit polyclonal antibody against GHRHR protein. Immunogen region is C-terminal.…
Ver producto
Growth Hormone Releasing Hormone Receptor (GHRHR) Antibody
GHRHR is a receptor for growth hormone-releasing hormone. Binding of this hormone to the receptor leads to synthesis and…
Ver producto