Glycophorin C (GYPC) Antibody

Este producto es parte de GYPC - glycophorin C
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260€ (50 µl)

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935106861
info@markelab.com
name
Glycophorin C (GYPC) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx210235
tested applications
ELISA, IHC

Description

GYPC Antibody is a Rabbit Polyclonal against GYPC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Glycophorin C (GYPC)
Host
Rabbit
Reactivity
Human
Recommended Dilution
ELISA: 1/2000 - 1/10000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Antigen Affinity Chromatography.
Size 1
50 µl
Size 2
100 µl
Form
Liquid
Tested Applications
ELISA, IHC
Buffer
PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P04921
Gene ID
2995
Alias
Gerbich blood group,GE,GPC,GPD,GYPD,CD236,PAS-2,CD236R,Glycoconnectin,Glycophorin-D,Glycoprotein beta,
Background
Antibody anti-GYPC
Status
RUO

Descripción

Glycophorin C (GYPC) is a membrane glycoprotein found primarily on the surface of red blood cells (RBCs). It is a member of the glycophorin family, which includes Glycophorin A (GYPA) and Glycophorin B (GYPB). GYPC plays a crucial role in maintaining the structural integrity of the RBC membrane and contributes to the MNS blood group system. The protein is encoded by the GYPC gene located on chromosome 2. Along with its homologs GYPA and GYPB, GYPC is involved in defining RBC membrane characteristics, including cell shape, flexibility, and interactions with the cytoskeleton. GYPC, specifically, is known to carry the M and N antigens of the MNS blood group system, which are significant in transfusion medicine. In addition to its structural function in the RBC membrane, GYPC plays a role in the function of the erythrocyte by interacting with various signaling molecules and maintaining the membrane's elasticity and resistance to mechanical stresses. Its functional importance in RBCs, as well as its potential relevance in certain disease states, makes it a significant protein in both clinical and biological research.

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