Glycine Receptor Alpha 1 and 2 (GLRA1/GLRA2) Antibody

Product Graph
663€ (200 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Glycine Receptor Alpha 1 and 2 (GLRA1/GLRA2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx412594
tested applications
WB, IHC

Description

Glycine Receptor Alpha 1 and 2 (GLRA1/GLRA2) Antibody is a Rabbit Polyclonal antibody against GLYCINE RECEPTOR ALPHA 1/2.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Glycine Receptor Alpha 1 and 2 (GLRA1/GLRA2)
Host
Rabbit
Reactivity
Rat
Recommended Dilution
Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified
Size 1
200 µg
Form
Lyophilized
Tested Applications
WB, IHC
Buffer
Ammonium bicarbonate
Availability
Shipped within 3-7 working days.
Storage
Store lyophilized at 2°C to 8°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P07727, P22771
Background
Antibody anti-GLRA1
Status
RUO

Descripción

Related Products

FNab03486

GLRA1 antibody

Glycine receptors are ligand-gated chloride channels(PubMed:23994010, PubMed:25730860). Channel opening is triggered by extracellular glycine(PubMed:2155780, PubMed:7920629, PubMed:14551753, PubMed:16144831, PubMed:22715885, PubMed:22973015, PubMed:25973519, PubMed:9009272). Channel opening is also triggered by taurine and beta-alanine(PubMed:16144831, PubMed:9009272). Channel characteristics depend on the subunit composition; heteropentameric channels are activated by lower glycine levels and display faster desensitization(PubMed:14551753). Plays an important role in the down-regulation of neuronal excitability(PubMed:8298642, PubMed:9009272). Contributes to the generation of inhibitory postsynaptic currents(PubMed:25445488). Channel activity is potentiated by ethanol(PubMed:25973519). Potentiation of channel activity by intoxicating levels ot ethanol contribute to the sedative effects of ethanol(By similarity).

Ver Producto
P8839

Recombinant Human GLRA1

Ver Producto
abx002153

Glycine Receptor Alpha 1 (GLRA1) Antibody

GLRA1 Antibody is a Rabbit Polyclonal antibody against GLRA1. Glycine receptor subunit alpha-1 is a protein that in humans is encoded by the GLRA1 gene. The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene.

Ver Producto