Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

253.5€ (100 µg)
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935106861
info@markelab.com
name
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx019088
tested applications
ELISA, WB, IF/ICC
Description
GAPDH Antibody is a Mouse Monoclonal antibody against Human and Monkey.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) |
Host | Mouse |
Reactivity | Human, Monkey |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 |
Size 1 | 100 µg |
Tested Applications | ELISA, WB, IF/ICC |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH |
Background | Antibody anti-GAPDH |
Status | RUO |
Descripción
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.
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