Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Este producto es parte de GAPDH - Glyceraldehyde-3-phosphate dehydrogenase
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Pida mas información

935106861

info@markelab.com

Precio

416€ (200 µl)

Antibody anti-GAPDH

proveedor

Abbexa

reference

abx431279

Tested Applications

P-ELISA, WB, IHC, IF/ICC

reactivity

Human, Mouse, Rat

status

RUO

clonality

Polyclonal

Descripción

GAPDH Antibody is a Goat Polyclonal antibody against GAPDH.

Background

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.

Características del producto

category

Primary Antibodies

clonality

Polyclonal

reactivity

Human, Mouse, Rat

immunogen target

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)

host

Goat

isotype

IgG

conjugation

Unconjugated

form

Liquid

tested applications

P-ELISA, WB, IHC, IF/ICC

purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

recommended dilution

P-ELISA: 1/16000, WB: 0.03-1 µg/ml, IHC: 2 µg/ml, IF/ICC: 5-10 µg/ml. Optimal dilutions/concentrations should be determined by the end user.

buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.

size 1

200 µl

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

GAPDH

dry ice

No

availability

Shipped within 5-10 working days.

alias

GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH

gene id

https://www.ncbi.nlm.nih.gov/gene/2597https://www.ncbi.nlm.nih.gov/gene/14433https://www.ncbi.nlm.nih.gov/gene/24383

NCBI accession

NP_002037.2, NP_001243728.1

note

Concentration: 0.5 mg/ml -

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