Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
364€ (100 µg)
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935106861
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name
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx233343
tested applications
ELISA, WB, IHC, IF/ICC, FCM, IP
Description
GAPDH Antibody is a Mouse Monoclonal against GAPDH.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) |
| Host | Mouse |
| Reactivity | Human, Mouse, Rat, Zebrafish |
| Recommended Dilution | WB: 1/5000 - 1/20000, IHC: 1/50 - 1/500, IF/ICC: 1/20 - 1/200, IP: 1/3000 - 1/20000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by Protein A and Protein G affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM, IP |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04406 |
| Gene ID | 2597 |
| NCBI Accession | NP_001243728.1 |
| Alias | GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH |
| Background | Antibody anti-GAPDH |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.
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