Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody
Pida mas información
935106861
info@markelab.com
Precio
299€ (100 µl)
Antibody anti-GAPDH
proveedor
Abbexareference
abx132230Tested Applications
WBreactivity
Human, Mouse, Rat, Guinea pig, Rabbit, Pig, Cow, Goat, Sheep, Chicken, Horsestatus
RUOclonality
MonoclonalDescripción
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody is a Mouse Monoclonal loading control antibody against Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH).
Background
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human, Mouse, Rat, Guinea pig, Rabbit, Pig, Cow, Goat, Sheep, Chicken, Horse
immunogen target
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)
host
Mouse
isotype
IgG1 Kappa
conjugation
Unconjugated
form
Liquid
tested applications
WB
purification
Purified by Protein A and Protein G affinity chromatography.
recommended dilution
WB: 0.1-100 ng/ml (1/10,000 - 1/10,000,000). Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
100 µl
size 2
200 µl
size 3
1 ml
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
GAPDH
dry ice
No
availability
Shipped within 5-7 working days.
alias
GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH
uniprot id
note
Concentration: 1 mg/ml -
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