Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Este producto es parte de GAPDH - Glyceraldehyde-3-phosphate dehydrogenase
Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH) Antibody

Pida mas información

935106861

info@markelab.com

Precio

286€ (100 µl)

Antibody anti-GAPDH

proveedor

Abbexa

reference

abx104161

Tested Applications

WB, IHC, IF/ICC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Polyclonal Antibody to Glyceraldehyde 3 phosphate dehydrogenase (GAPDH) (GAPDH).


Background

Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a multifunctional enzyme predominantly involved in glycolysis, catalyzing the oxidative phosphorylation of glyceraldehyde-3-phosphate to 1,3-bisphosphoglycerate using NAD+ as a cofactor. Beyond its metabolic role, GAPDH participates in various non-metabolic processes, including transcriptional regulation, DNA repair, and cell apoptosis. Its involvement in oxidative stress response and as a target for S-nitrosylation connects it to neurodegenerative diseases such as Alzheimer's and Parkinson's. Furthermore, GAPDH can translocate to the nucleus under stress conditions, influencing apoptotic pathways.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Glyceraldehyde-3-Phosphate Dehydrogenase (GAPDH)


host

Rabbit


conjugation

Unconjugated


form

Liquid


tested applications

WB, IHC, IF/ICC


purification

Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.


recommended dilution

WB: 0.01-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.


size 1

100 µl


size 2

200 µl


size 3

1 ml


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

GAPDH


dry ice

No


availability

Shipped within 5-7 working days.


alias

GAPDH, GAPD, G3PD, HEL-S-162eP,Peptidyl-cysteine S-nitrosylase GAPDH


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