GDP-Fucose Protein O-Fucosyltransferase 2 (POFUT2) Antibody
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Description
GDP-Fucose Protein O-Fucosyltransferase 2 (POFUT2) Antibody is a Rabbit polyclonal antibody for the detection of Human GDP-Fucose Protein O-Fucosyltransferase 2 (POFUT2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | GDP-Fucose Protein O-Fucosyltransferase 2 (POFUT2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y2G5 |
| Gene ID | 23275 |
| NCBI Accession | NP_056042.1 |
| Background | Antibody anti-POFUT2 |
| Status | RUO |
Descripción
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Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin(TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition(EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm(By similarity). Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.
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