Gastric Inhibitory Polypeptide Receptor (GIPR) Antibody
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Description
Gastric Inhibitory Polypeptide Receptor (GIPR) Antibody is a Rabbit polyclonal antibody for the detection of Mouse Gastric Inhibitory Polypeptide Receptor (GIPR).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Gastric Inhibitory Polypeptide Receptor (GIPR) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q0P543 |
| NCBI Accession | NP_001074284.1 |
| Alias | PGQTL2,Gippr,GIP-R |
| Background | Antibody anti-GIPR |
| Status | RUO |
Descripción
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GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
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