Gastric Inhibitory Peptide (GIP)

Este producto es parte de GIP - Gastric inhibitory polypeptide ( Receptor)
Gastric Inhibitory Peptide (GIP)
390€ (1 mg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Gastric Inhibitory Peptide (GIP)
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx265278

Description

Gastric Inhibitory Peptide (GIP) is a peptide.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Proteins and Peptides
Immunogen Target
Gastric Inhibitory Peptide (GIP)
Origin
Human
Conjugation
Unconjugated
Observed MW
4983.64 Da
Purity
> 95% (HPLC)
Size 1
1 mg
Size 2
2.5 mg
Form
Lyophilized
Buffer
Not applicable.
Availability
Shipped within 10-20 working days.
Storage
Store dry at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
Glucose-dependent insulinotropic polypeptide,Incretin
Background
Protein GIP
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

GIP, also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid hormone secreted by K-cells in the duodenum and jejunum in response to nutrient ingestion, particularly glucose, fats, and amino acids GIP acts as a critical incretin hormone that enhances glucose-dependent insulin secretion from pancreatic β-cells by activating cAMP-dependent pathways and protein kinase A signaling GIP also regulates lipid metabolism by stimulating lipoprotein lipase activity in adipose tissue, promoting triglyceride uptake and energy storage GIP further supports bone homeostasis by enhancing osteoblast function, contributing to bone formation and mineralization Dysregulation of GIP levels and signaling is associated with insulin resistance, obesity, and type 2 diabetes where its insulinotropic effects are impaired despite elevated circulating levels GIP-based therapies, including dual GIP/GLP-1 receptor agonists, have shown therapeutic potential in improving glycemic control and promoting weight loss in metabolic disorders

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