Gamma-Glutamylcyclotransferase (GGCT) Antibody
364€ (100 µg)
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935106861
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name
Gamma-Glutamylcyclotransferase (GGCT) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx233443
tested applications
ELISA, WB, IHC
Description
GGCT Antibody is a Rabbit Polyclonal against GGCT.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Gamma-Glutamylcyclotransferase (GGCT) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000, IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purity | ≥ 95% (SDS-PAGE) |
| Purification | Purified by immunogen affinity chromatography. |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O75223 |
| Gene ID | 79017 |
| OMIM | 137170 |
| Alias | GGC,GCTG,CRF21,C7orf24,Cytochrome c-releasing factor 21 |
| Background | Antibody anti-GGCT |
| Status | RUO |
| Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
Gamma Glutamyl Cyclotransferase (GGCT) is an enzyme that plays a crucial role in glutathione metabolism by catalyzing the conversion of gamma-glutamyl peptides to 5-oxoproline and free amino acids. GGCT is involved in maintaining cellular redox balance and regulating glutathione homeostasis, which is essential for cellular protection against oxidative stress and detoxification processes. Dysregulation of GGCT activity has been linked to various pathological conditions, including cancer, where it is often upregulated and contributes to tumor proliferation and chemoresistance. Its role in the gamma-glutamyl cycle also makes it a potential target for therapeutic interventions in oxidative stress-related diseases.
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