Gamma-Glutamylcyclotransferase (GGCT) Antibody
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935106861
info@markelab.com
Precio
637€ (100 µl)
Antibody anti-GGCT
proveedor
Abbexareference
abx116838Tested Applications
ELISA, WBreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
Gamma-Glutamyl Cyclotransferase Polyclonal Antibody is a Rabbit Polyclonal antibody against Gamma-Glutamyl Cyclotransferase Polyclonal Antibody.
Background
Gamma Glutamyl Cyclotransferase (GGCT) is an enzyme that plays a crucial role in glutathione metabolism by catalyzing the conversion of gamma-glutamyl peptides to 5-oxoproline and free amino acids. GGCT is involved in maintaining cellular redox balance and regulating glutathione homeostasis, which is essential for cellular protection against oxidative stress and detoxification processes. Dysregulation of GGCT activity has been linked to various pathological conditions, including cancer, where it is often upregulated and contributes to tumor proliferation and chemoresistance. Its role in the gamma-glutamyl cycle also makes it a potential target for therapeutic interventions in oxidative stress-related diseases.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Gamma-Glutamylcyclotransferase (GGCT)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
ELISA, WB
purification
Antigen Affinity Chromatography.
recommended dilution
Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.1% Sodium Azide and 50% Glycerol.
size 1
100 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
GGCT
dry ice
No
availability
Shipped within 5-10 working days.
alias
GGC,GCTG,CRF21,C7orf24,Cytochrome c-releasing factor 21
uniprot id
NCBI accession
NP_001186744.1, NM_001199815.1, NP_001186745.1, NM_001199816.1, NP_001186746.1, NM_001199817.1, NP_076956.1, NM_024051.3
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