Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx326691
tested applications
ELISA, IHC
Description
B3GAT1 Antibody is a Rabbit Polyclonal against B3GAT1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 (B3GAT1) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | ELISA: 1/5000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9P2W7 |
| Gene ID | 27087 |
| Alias | NK1,CD57,HNK1,LEU7,NK-1,GLCATP,GLCUATP,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,Beta-1,3-glucuronyltransferase 1,Glucuronosyltransferase P,UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase,GlcUAT-P |
| Background | Antibody anti-B3GAT1 |
| Status | RUO |
Descripción
Beta-1,3-Glucuronyltransferase 1 (B3GAT1) is an enzyme encoded by the B3GAT1 gene, which plays a critical role in glycosylation processes. It belongs to the family of glycosyltransferases, a group of enzymes responsible for the biosynthesis of glycosaminoglycans (GAGs) and other complex carbohydrates. Specifically, B3GAT1 is involved in the synthesis of the carbohydrate moiety known as the HNK-1 epitope, a unique glycan structure that is found on several proteins in the nervous system and involved in cell-cell and cell-matrix interactions. The enzyme adds a glucuronic acid moiety to the core glycan structure, which is a crucial step in the formation of these specialized carbohydrate chains. B3GAT1 is particularly important in the central nervous system (CNS), where the HNK-1 epitope is associated with neurodevelopmental processes such as cell adhesion, synaptic plasticity, and neuronal migration. The enzyme is also expressed in other tissues, including lymphoid tissues, indicating a broader role in immune regulation and cell signaling.
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