Forkhead Box Protein P2 (FOXP2) Antibody

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Description
FOXP2 Antibody is a Mouse Monoclonal against FOXP2.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Forkhead Box Protein P2 (FOXP2) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | ELISA: 1/10000, WB: 1/500 - 1/2000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Isotype | IgG1 |
Purification | Purified from ascites by Protein G chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB, FCM |
Buffer | PBS, containing 0.05% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | O15409 |
Gene ID | 93986 |
OMIM | 602081 |
Background | Antibody anti-FOXP2 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors.It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut.The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes.This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development.Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia.Multiple alternative transcripts encoding different isoforms have been identified in this gene.
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