Fatty Aldehyde Dehydrogenase (ALDH3A2) Antibody
442€ (200 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Fatty Aldehyde Dehydrogenase (ALDH3A2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx431090
tested applications
P-ELISA, WB, IHC
Description
ALDH3A2 Antibody is a Goat Polyclonal antibody against ALDH3A2.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Fatty Aldehyde Dehydrogenase (ALDH3A2) Immunogen: abx616288 - Internal region: C-KGLKGESVNKLRY |
| Host | Goat |
| Reactivity | Human, Rat |
| Assay Type | Concentration: 0.5 mg/ml |
| Recommended Dilution | P-ELISA: 1/32000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 11671, 65183 |
| NCBI Accession | NP_113919.2 |
| Alias | ALDH3A2,ALDH10,FALDH |
| Background | Antibody anti-ALDH3A2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
ALDH3A2, also known as fatty aldehyde dehydrogenase (FALDH), is a key enzyme that catalyzes the oxidation of fatty aldehydes to fatty acids. This process is essential for lipid metabolism, particularly in the breakdown of long-chain and very-long-chain fatty aldehydes derived from sphingolipids and dietary fats. Mutations in ALDH3A2 cause Sjögren-Larsson Syndrome (SLS), a rare autosomal recessive disorder characterized by ichthyosis (skin scaling), spasticity, and intellectual disability due to the accumulation of fatty aldehydes and disruption of lipid homeostasis. ALDH3A2 is expressed in the liver, brain, and skin, where it supports lipid metabolism and protects against oxidative stress. Its role in maintaining cellular membrane integrity and energy balance highlights its importance in metabolic and neuroprotective functions. Therapies targeting ALDH3A2 aim to restore fatty acid metabolism and alleviate symptoms of SLS, emphasizing its role in lipid-mediated pathologies.
Related Products
Fatty Aldehyde Dehydrogenase (ALDH3A2) Peptide
Fatty Aldehyde Dehydrogenase (ALDH3A2) Peptide is a synthetic peptide. This peptide is used in the production of
Ver Producto