Fas Activated Serine/Threonine Kinase (FASTK) Antibody

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Description
FASTK Antibody is a Rabbit Polyclonal against FASTK.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Fas Activated Serine/Threonine Kinase (FASTK) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 20 µl |
Size 2 | 50 µl |
Size 3 | 100 µl |
Size 4 | 200 µl |
Size 5 | 1 ml |
Form | Liquid |
Tested Applications | ELISA, IHC |
Buffer | PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q14296 |
Gene ID | 10922 |
NCBI Accession | NP_001245390.1, NM_001258461.1, NP_006703.1, NM_006712.4 |
OMIM | 606965 |
Background | Antibody anti-FASTK |
Status | RUO |
Descripción
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FASTK Antibody is a Rabbit Polyclonal antibody against FASTK. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
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