Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) Antibody

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Description
4EBP1 Antibody is a Mouse Monoclonal against 4EBP1.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Eukaryotic Translation Initiation Factor 4E-Binding Protein 1 (4EBP1) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 1/500 - 1/2000, IF/ICC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2b |
Purity | ≥ 95% (SDS-PAGE) |
Purification | Purified by Protein A and Protein G affinity chromatography. |
Size 1 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, WB, IF/ICC |
Buffer | PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol. |
Availability | Shipped within 5-12 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q13541 |
Gene ID | 1978 |
OMIM | 602223 |
Alias | 4E-BP1,4EBP1,BP-1,PHAS-I |
Background | Antibody anti-EIF4EBP1 |
Status | RUO |
Note | Concentration: 2 mg/ml - Validity: 12 months. |
Descripción
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Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
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Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
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Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
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