ErbB2 Protein

Este producto es parte de ERBB2 - erb-b2 receptor tyrosine kinase 2
Product Graph
10881€ (1 mg)

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935106861
info@markelab.com
name
ErbB2 Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx061452
tested applications
ELISA

Description

ErbB2  Protein is a recombinant Protein. It is produced using HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
ErbB2
Host
Human
Expression
Recombinant
Purification
Purified from HEK293 cells
Size 1
1 mg
Form
Lyophilized
Tested Applications
ELISA
Buffer
Buffer contains no preservative.
Availability
Shipped within 10-20 working days.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
Receptor tyrosine-protein kinase erbB-2,NEU,NGL,HER2,TKR1,CD340,HER-2,VSCN2,MLN 19,MLN-19,c-ERB2,c-ERB-, HER-2/neu; p185(erbB2),Metastatic lymph node gene 19 protein,Proto-oncogene Neu,Proto-oncogene c-ErbB-2,Tyrosine kinase-type cell surface,p185erbB2 receptor HER2
Background
Protein ERBB2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

ERBB2, also known as HER2 (human epidermal growth factor receptor 2), is a receptor tyrosine kinase that is part of the ERBB receptor family. This family consists of four closely related receptors: EGFR (ERBB1), HER2 (ERBB2), HER3 (ERBB3), and HER4 (ERBB4). These receptors play crucial roles in cellular signaling pathways regulating cell growth, differentiation, survival, and apoptosis. ERBB2 is particularly significant due to its role in breast cancer and other cancers, where its overexpression or gene amplification is associated with aggressive tumor behavior and poor prognosis. ERBB2 lacks a direct ligand-binding domain but acts as a co-receptor to enhance signaling when paired with other ERBB family members. Its importance in oncology has led to the development of therapies targeting HER2, such as monoclonal antibodies and tyrosine kinase inhibitors.

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