Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody
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Description
Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) Antibody is a Mouse Monoclonal antibody for the detection of Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) in Human samples.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Epithelial Discoidin Domain-Containing Receptor 1 (DDR1) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | T826 |
| Purity | > 95% (SDS-PAGE) |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | 0.01 M PBS, pH 7.4, 0.09% Sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q08345 |
| Gene ID | 780 |
| NCBI Accession | NP_001189450.1 |
| Alias | Epithelial discoidin domain-containing receptor 1,Epithelial discoidin domain receptor 1,CA, DDR,NEP,HGK2,PTK3,RTK6,TRKE,CD167,EDDR1,MCK10,NTRK4,PTK3A,Discoidin receptor tyrosine kinase,Mammary carcinoma kinase 10 |
| Background | Antibody anti-DDR1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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anti- DDR1 antibody
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
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anti- DDR1 antibody
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell migration and wound healing. Required for normal blastocyst implantation during pregnancy, for normal mammary gland differentiation and normal lactation. Required for normal ear morphology and normal hearing(By similarity). Promotes smooth muscle cell migration, and thereby contributes to arterial wound healing. Also plays a role in tumor cell invasion. Phosphorylates PTPN11.
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