Epidermal Growth Factor Receptor (EGFR) Antibody

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559€ (100 µl)

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935106861
info@markelab.com
name
Epidermal Growth Factor Receptor (EGFR) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025549
tested applications
ELISA, WB

Description

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. This antibody is supplied as crude ascites.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Epidermal Growth Factor Receptor (EGFR)
Host
Mouse
Reactivity
Human
Recommended Dilution
WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG1 Kappa
Purification
Unpurified crude ascites.
Size 1
100 µl
Form
Liquid
Tested Applications
ELISA, WB
Buffer
Ascites containing 0.09% sodium azide.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P00533
NCBI Accession
NP_005219.2, NP_958439.1, NP_958440.1, NP_958441.1
Background
Antibody anti-EGFR
Status
RUO

Descripción

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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

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