Epidermal Growth Factor Receptor (EGFR) Antibody

559€ (100 µl)
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935106861
info@markelab.com
name
Epidermal Growth Factor Receptor (EGFR) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx025549
tested applications
ELISA, WB
Description
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. This antibody is supplied as crude ascites.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | Epidermal Growth Factor Receptor (EGFR) |
Host | Mouse |
Reactivity | Human |
Recommended Dilution | WB: 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG1 Kappa |
Purification | Unpurified crude ascites. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB |
Buffer | Ascites containing 0.09% sodium azide. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P00533 |
NCBI Accession | NP_005219.2, NP_958439.1, NP_958440.1, NP_958441.1 |
Background | Antibody anti-EGFR |
Status | RUO |
Descripción
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EGFR antibody
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Ver Producto