Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibody
292.5€ (80 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx033192
tested applications
ELISA, WB
Description
ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q76MJ5 |
| Gene ID | 10595 |
| Background | Antibody anti-ERN2 |
| Status | RUO |
| Note | Concentration: 2 mg/ml - |
Descripción
Related Products
Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibody
ERN2 induces translational repression through 28S ribosomal RNA cleavage in response to endoplasmic reticulum (ER) stress. This pro-apoptotic appears to play no role in the unfolded-protein response, unlike closely related proteins. Overexpression of ERN2 activates both BiP and CHOP expression, and also leads to the development of programmed cell death. It has been suggested that Ern2 plays a role in multiple facets of the ER stress response in mammalian cells.
Ver Producto
Endoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibody
ERN2 Antibody is a Rabbit Polyclonal against ERN2.
Ver ProductoEndoplasmic Reticulum To Nucleus Signaling 2 (ERN2) Antibody
ERN2 Antibody is a Rabbit Polyclonal against ERN2.
Ver Producto