Endoglin (ENG) Antibody
312€ (50 µg)
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name
Endoglin (ENG) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421010
tested applications
FCM
Description
Endoglin (ENG) Antibody is a Human Monoclonal antibody for the detection of Endoglin (ENG) in Human samples.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Endoglin (ENG) |
| Host | Human |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 Kappa |
| Clone ID | E251 |
| Purity | > 95% |
| Purification | Purified by Protein A/G affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
| Dry Ice | No |
| UniProt ID | P17813 |
| Gene ID | 2022 |
| NCBI Accession | NP_000109.1 |
| Alias | END,HHT1,ORW1,CD105 |
| Background | Antibody anti-ENG |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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ENG antibody
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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