Endoglin / CD105 (ENG) Antibody (APC)
429€ (100 tests)
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935106861
info@markelab.com
name
Endoglin / CD105 (ENG) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx347256
tested applications
FCM
Description
Endoglin / CD105 (ENG) Antibody (APC) is a APC-conjugated Mouse monoclonal antibody for the detection of Endoglin / CD105 (ENG).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Endoglin / CD105 (ENG) |
| Host | Mouse |
| Reactivity | Human, Pig |
| Recommended Dilution | FCM: 10 µl/100 µl whole blood or 106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG2a |
| Clone ID | K942 |
| Purification | Purified by size-exclusion chromatography. |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | PBS, pH 7.4, 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C in the dark. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P17813 |
| Gene ID | 2022 |
| Alias | END,HHT1,ORW1,CD105 |
| Background | Antibody anti-ENG |
| Status | RUO |
Descripción
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ENG antibody
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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