Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) Antibody
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Description
ENPP2 Antibody is a Goat Polyclonal antibody against ENPP2.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2) |
| Host | Goat |
| Reactivity | Human |
| Recommended Dilution | P-ELISA: 1/128000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Size 1 | 200 µl |
| Form | Liquid |
| Tested Applications | P-ELISA, WB, IHC |
| Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 5168 |
| NCBI Accession | NP_006200.3, NP_001035181.1, NP_001124335.1 |
| Background | Antibody anti-ENPP2 |
| Status | RUO |
| Note | Concentration: 0.5 mg/ml - |
Descripción
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ENPP2 antibody
Hydrolyzes lysophospholipids to produce lysophosphatidic acid(LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor.
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