E3 Ubiquitin-Protein Ligase RNF6 (RNF6) Antibody

260€ (50 µg)
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935106861
info@markelab.com
name
E3 Ubiquitin-Protein Ligase RNF6 (RNF6) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx457490
tested applications
ELISA, WB, IHC
Description
E3 Ubiquitin-Protein Ligase RNF6 (RNF6) Antibody is a Rabbit polyclonal antibody for the detection of Human E3 Ubiquitin-Protein Ligase RNF6 (RNF6).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | E3 Ubiquitin-Protein Ligase RNF6 (RNF6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9Y252 |
| Gene ID | 6049 |
| NCBI Accession | NP_005968.1 |
| Background | Antibody anti-RNF6 |
| Status | RUO |
Descripción
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RNF6 antibody
E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
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