E3 Ubiquitin-Protein Ligase CBL (CBL) Peptide
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
E3 Ubiquitin-Protein Ligase CBL (CBL) Peptide is a synthetic peptide.
Documents del producto
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | E3 Ubiquitin-Protein Ligase CBL (CBL) |
| Host | Synthetic |
| Recommended Dilution | BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Observed MW | Sequence Fragment: C-Terminus: C-REFVSISSPAHVAT |
| Size 1 | 100 µg |
| Form | Lyophilized Reconstitute in deionized water. |
| Tested Applications | P-ELISA |
| Buffer | Prior to lyophilization: Deionized water. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Gene ID | 867, 12402 |
| NCBI Accession | NP_005179.2 |
| Alias | CBL, C-CBL2, FRA11B, NSLL, RNF55 |
| Background | Protein CBL |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Related Products
CBL antibody
This gene is a proto-oncogene that encodes a RING finger E3 ubiquitin ligase. The encoded protein is one of the enzymes required for targeting substrates for degradation by the proteasome. This protein mediates the transfer of ubiquitin from ubiquitin conjugating enzymes (E2) to specific substrates. This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation. As such it functions as a negative regulator of many signal transduction pathways. This gene has been found to be mutated or translocated in many cancers including acute myeloid leukaemia, and expansion of CGG repeats in the 5' UTR has been associated with Jacobsen syndrome. Mutations in this gene are also the cause of Noonan syndrome-like disorder.
Ver Producto
Recombinant Human CBL
Ver Producto
E3 Ubiquitin-Protein Ligase CBL (CBL) Antibody
Rabbit Polyclonal against the CBL protein.
Ver Producto