E3 ISG15--protein ligase HERC5 (HERC5) Antibody (Biotin)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
E3 ISG15--protein ligase HERC5 (HERC5) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin for the detection of Human HERC5.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | E3 ISG15--protein ligase HERC5 (HERC5) |
Host | Rabbit |
Reactivity | Human |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Biotin |
Isotype | IgG |
Purity | > 95% |
Purification | Purified by Protein G chromatography. |
Size 1 | 20 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 1 mg |
Form | Liquid |
Tested Applications | ELISA |
Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | Q9UII4 |
Gene ID | 51191 |
OMIM | 608242 |
Background | Antibody anti-HERC5 |
Status | RUO |
Descripción
Related Products

HERC5 antibody
Major E3 ligase for ISG15 conjugation. Acts as a positive regulator of innate antiviral response in cells induced by interferon. Functions as part of the ISGylation machinery that recognizes target proteins in a broad and relatively non-specific manner. Catalyzes ISGylation of IRF3 which results in sustained activation, it attenuates IRF3-PIN1 interaction, which antagonizes IRF3 ubiquitination and degradation, and boosts the antiviral response. Catalyzes ISGylation of influenza A viral NS1 which attenuates virulence; ISGylated NS1 fails to form homodimers and thus to interact with its RNA targets. Catalyzes ISGylation of papillomavirus type 16 L1 protein which results in dominant-negative effect on virus infectivity. Physically associated with polyribosomes, broadly modifies newly synthesized proteins in a cotranslational manner. In an interferon-stimulated cell, newly translated viral proteins are primary targets of ISG15.
Ver Producto
Recombinant Human HERC5
Ver Producto
Human HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 5 (HERC5) Protein
HECT And RLD Domain Containing E3 Ubiquitin Protein Ligase 5 is a recombinant enzyme.
Ver Producto