Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Peptide

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175.5€ (100 µg)

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935106861
info@markelab.com
name
Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx616798
tested applications
P-ELISA

Description

Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A) Peptide is a synthetic peptide.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1A (DYRK1A)
Host
Synthetic
Recommended Dilution
BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Unconjugated
Observed MW
Sequence Fragment: N-Terminus: PHSHQYSDRRQPN-C
Size 1
100 µg
Form
Lyophilized Reconstitute in deionized water.
Tested Applications
P-ELISA
Buffer
Prior to lyophilization: Deionized water.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
1859, 13548, 25255
NCBI Accession
NP_001387.2, NP_569120.1, NP_567824.1, NP_569122.1
Background
Protein DYRK1A
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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DYRK1A is a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidine repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development. This gene is a homolog of Drosophila mnb (minibrain) gene and rat Dyrk gene. It is localized in the Down syndrome critical region of chromosome 21, and is considered to be a strong candidate gene for learning defects associated with Down syndrome.

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