Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Antibody
299€ (50 µl)
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name
Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx402541
tested applications
ELISA, WB, IHC, IP
Description
Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human, Rat MAP2K1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Dual Specificity Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/500 - 1/5000, IHC: 1/50 - 1/200, IP: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IP |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q02750 |
| Gene ID | 5604 |
| NCBI Accession | NP_002746.1 |
| Background | Antibody anti-MAP2K1 |
| Status | RUO |
Descripción
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MEK1 is also named as MAP2K1(mitogen-activated protein kinase kinase 1), MAPKK1, PRKMK1, MKK1 and belongs to the MAP kinase kinase subfamily. It is a dual-specificity kinase that mediate ERK1 and ERK2 activation during adhesion and growth factor signaling(PMID:19219045). It also plays an essential role in extra-embryonic ectoderm during placentogenesis. MEK1 has 2 isoforms produced by alternative splicing with the molecular weight of 43 kDa and 41 kDa. It can be phosphorylated.
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