Double-Strand Break Repair Protein MRE11 (MRE11) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Double-Strand Break Repair Protein MRE11 (MRE11) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx001996
tested applications
WB
Description
MRE11 Antibody is a Rabbit Polyclonal antibody against MRE11. This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Double-Strand Break Repair Protein MRE11 (MRE11) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49959 |
| Gene ID | 4361 |
| NCBI Accession | NP_005581.2, NM_005590.3, NP_005582.1, NM_005591.3 |
| OMIM | 600814 |
| Background | Antibody anti-MRE11 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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