Dog Transferrin Receptor Protein 1 / CD71 (TFRC) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Dog Transferrin Receptor Protein 1 / CD71 (TFRC) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx514057
Tested Applications
ELISA
Description
Dog Transferrin Receptor Protein 1 / CD71 (TFRC) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Dog Transferrin Receptor Protein 1 / CD71 (TFRC) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Transferrin Receptor Protein 1 / CD71 (TFRC) |
| Reactivity | Dog |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9GLD3 |
| Alias | CD71,IMD46,T9,TFR,TFR1,TR,TRFR,p90 |
| Background | Elisa Kits for: TFRC |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
TFRC, also known as CD71, is a transmembrane glycoprotein that mediates the uptake of transferrin-bound iron into cells via receptor-mediated endocytosis. It plays a crucial role in iron homeostasis, as iron is essential for processes like DNA synthesis, oxygen transport, and energy metabolism. TFRC expression is tightly regulated by cellular iron levels, proliferative demand, and hypoxia, with high expression observed in rapidly dividing cells, such as activated lymphocytes, erythroid progenitors, and cancer cells. Its overexpression is frequently observed in tumors, where increased iron uptake supports cancer cell proliferation and survival. TFRC is also involved in immune regulation and erythropoiesis, with its deficiency leading to anemia, impaired cell growth, and compromised immune responses. Targeting TFRC is being explored in cancer therapy as a mechanism for selective drug delivery and iron deprivation. Knockdown studies show impaired iron metabolism, reduced cell proliferation, and increased sensitivity to oxidative stress, emphasizing its central role in cellular growth, iron transport, and metabolic regulation.
Productos relacionados
Transferrin Receptor Protein 1 / CD71 (TFRC) Antibody
Transferrin Receptor Protein 1 / CD71 (TFRC) Antibody is a Rabbit Polyclonal antibody against Transferrin Receptor Prote…
Ver producto
Transferrin Receptor Protein 1 / CD71 (TFRC) Antibody
CD71 Transferrin Receptor Antibody is a Mouse monoclonal antibody for human cds against CD71 Transferrin Receptor.…
Ver producto
Transferrin Receptor Protein 1 / CD71 (TFRC) Antibody
CD71 TRANSFERRIN RECEPT Antibody is a Monoclonal Antibody to Human CDs.…
Ver producto