Dog CAMPATH-1 Antigen (CD52) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CD52
proveedor
Abbexareference
abx515371Tested Applications
ELISAreactivity
Dogstatus
RUOclonality
Descripción
Dog CAMPATH-1 Antigen (CD52) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Dog CAMPATH-1 Antigen (CD52) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CD52 is a small glycoprotein predominantly expressed on the surface of mature lymphocytes (both T and B cells), monocytes, macrophages, eosinophils, and some epithelial cells of the reproductive system. The CD52 molecule plays an important role in regulating immune cell function, and its high expression on lymphocytes makes it a valuable therapeutic target in immunology and oncology, particularly in treatments for autoimmune diseases and certain types of leukemia, such as chronic lymphocytic leukemia (CLL). The precise function of CD52 remains somewhat unclear, although it is believed to be involved in modulating immune responses and cellular interactions. CD52 is the target of the monoclonal antibody alemtuzumab, a treatment used in autoimmune conditions like multiple sclerosis (MS) and certain cancers like CLL. Alemtuzumab binds to CD52 on the surface of immune cells and triggers their destruction through immune-mediated mechanisms, leading to immunosuppression. This therapeutic aspect has drawn attention to the biological and clinical significance of the CD52 molecule.
Características del producto
category
ELISA Kits
immunogen target
CAMPATH-1 Antigen (CD52)
reactivity
Dog
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
HE5,CDW52,EDDM5,CAMPATH-1 antigen,Cambridge pathology 1,Epididymal secretory protein E5,Human epididymis-specific protein 5
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CD52
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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