Docking Protein 5 (DOK5) Antibody

Este producto es parte de DOK - Docking protein
Docking Protein 5 (DOK5) Antibody

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935106861

info@markelab.com

Precio

387.5€ (200 µl)

Antibody anti-DOK5

proveedor

Abbexa

reference

abx432205

Tested Applications

P-ELISA, WB, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

DOK5 Antibody is a Goat Polyclonal antibody against DOK5.


Background

DOK5 is a member of the DOK family, functioning as an adaptor protein in signaling pathways downstream of RET and insulin receptors. It is expressed in skeletal muscle, heart, and nervous tissue, where it regulates processes like cell survival, differentiation, and metabolic signaling. DOK5 enhances insulin signaling by activating the MAPK/ERK pathway but does not influence the PI3K/Akt pathway. It is critical for neurite outgrowth and neuronal development, particularly in response to neurotrophic factors. Dysregulation of DOK5 contributes to insulin resistance and is implicated in neurological disorders, where it affects neuronal survival and axonal guidance.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Docking Protein 5 (DOK5)


host

Goat


conjugation

Unconjugated


form

Liquid


tested applications

P-ELISA, WB, IHC


purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.


buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.


size 1

200 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

DOK5


dry ice

No


availability

Shipped within 1-3 working days.


alias

Downstream of tyrosine kinase 5,C20orf180,IRS-6,IRS6,Insulin receptor substrate 6


NCBI accession

NP_060901.2


note

This product is for research use only.


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