DNA Ligase 4 Phospho-Thr650 (LIG4 pT650) Antibody
221€ (50 µg)
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935106861
info@markelab.com
name
DNA Ligase 4 Phospho-Thr650 (LIG4 pT650) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx322874
tested applications
ELISA, IHC
Description
LIG4 (pT650) Antibody is a Rabbit Polyclonal against LIG4 (pT650).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA Ligase 4 Phospho-Thr650 (LIG4 pT650) |
| Host | Rabbit |
| Reactivity | Human |
| Assay Data | Modification: Phosphorylation // Target Modification: Thr650 |
| Recommended Dilution | ELISA: 1/10000, IHC: 1/100 - 1/300. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49917 |
| Gene ID | 3981 |
| Background | Antibody anti-LIG4 |
| Status | RUO |
Descripción
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Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining(NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
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