DNA Ligase 4 (LIG4) Antibody
260€ (50 µg)
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name
DNA Ligase 4 (LIG4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455465
tested applications
ELISA, WB, IHC
Description
DNA Ligase 4 (LIG4) Antibody is a Rabbit polyclonal antibody for the detection of Human DNA Ligase 4 (LIG4).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA Ligase 4 (LIG4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to 2 weeks. For long-term storage, aliquot and store at -80 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P49917 |
| Gene ID | 3981 |
| NCBI Accession | NP_001091738.1 |
| Background | Antibody anti-LIG4 |
| Status | RUO |
Descripción
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LIG4 antibody
Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining(NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
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