DNA Excision Repair Protein ERCC-1 (ERCC1) Antibody (FITC)
169€ (20 µg)
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935106861
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name
DNA Excision Repair Protein ERCC-1 (ERCC1) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx312716
Description
ERCC1 Antibody (FITC) is a Rabbit Polyclonal against ERCC1 conjugated to FITC.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA Excision Repair Protein ERCC-1 (ERCC1) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purity | > 95% |
| Purification | Purified by Protein G. |
| Size 1 | 20 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 1 mg |
| Form | Liquid |
| Buffer | 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07992 |
| Gene ID | 2067 |
| NCBI Accession | NP_001159521.1, NM_001166049.1, NP_001974.1, NM_001983.3 |
| OMIM | 126380 |
| Background | Antibody anti-ERCC1 |
| Status | RUO |
Descripción
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ERCC1 antibody
Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links(ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair(HDR) of DNA double-strand breaks, in conjunction with SLX4.
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