DNA Excision Repair Protein ERCC-1 (ERCC1) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
DNA Excision Repair Protein ERCC-1 (ERCC1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx224155
tested applications
ELISA, IF/ICC, FCM
Description
ERCC1 Antibody is a Mouse Monoclonal against ERCC1.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | DNA Excision Repair Protein ERCC-1 (ERCC1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IF/ICC, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P07992 |
| Gene ID | 2067 |
| OMIM | 126380 |
| Background | Antibody anti-ERCC1 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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ERCC1 antibody
Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links(ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair(HDR) of DNA double-strand breaks, in conjunction with SLX4.
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