Disrupted In Schizophrenia 1 Protein (DISC1) Antibody (Biotin)
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935106861
info@markelab.com
Precio
162.5€ (20 µg)
Antibody anti-DISC1
proveedor
Abbexareference
abx315164Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDescripción
DISC1 Antibody (Biotin) is a Rabbit Polyclonal against DISC1 conjugated to Biotin.
Background
Disrupted in schizophrenia 1 (DISC1) is a scaffolding protein with diverse roles in neurodevelopment, synaptic function, and adult neurogenesis. Originally identified in a Scottish family with a high incidence of schizophrenia, DISC1 has since been implicated in several psychiatric disorders, including bipolar disorder and major depression. DISC1 interacts with multiple molecular partners, influencing signaling pathways involved in neuronal proliferation, migration, and axonal growth. Additionally, it regulates mitochondrial function and intracellular trafficking. Dysfunctional DISC1 has been associated with structural brain abnormalities, synaptic deficits, and altered neuronal connectivity, which are common features in neuropsychiatric disorders. The multifaceted roles of DISC1 in cellular processes and its potential as a biomarker or therapeutic target underscore its significance in neuroscience and psychiatry research.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human
immunogen target
Disrupted In Schizophrenia 1 Protein (DISC1)
host
Rabbit
conjugation
Biotin
form
Liquid
tested applications
ELISA
purity
> 95%
purification
Purified by Protein G.
buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
size 1
20 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
1 mg
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
DISC1
dry ice
No
availability
Shipped within 5-10 working days.
alias
DISC1, C1orf136, SCZD9, disrupted in schizophrenia 1, DISC1 scaffold protein
uniprot id
NCBI accession
NM_018662.2
note
This product is for research use only.
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