Disrupted In Schizophrenia 1 Protein (DISC1) Antibody (Biotin)

Este producto es parte de DISC1 Scaffold Protein
Disrupted In Schizophrenia 1 Protein (DISC1) Antibody (Biotin)

Pida mas información

935106861

info@markelab.com

Precio

162.5€ (20 µg)

Antibody anti-DISC1

proveedor

Abbexa

reference

abx315164

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

DISC1 Antibody (Biotin) is a Rabbit Polyclonal against DISC1 conjugated to Biotin.


Background

Disrupted in schizophrenia 1 (DISC1) is a scaffolding protein with diverse roles in neurodevelopment, synaptic function, and adult neurogenesis. Originally identified in a Scottish family with a high incidence of schizophrenia, DISC1 has since been implicated in several psychiatric disorders, including bipolar disorder and major depression. DISC1 interacts with multiple molecular partners, influencing signaling pathways involved in neuronal proliferation, migration, and axonal growth. Additionally, it regulates mitochondrial function and intracellular trafficking. Dysfunctional DISC1 has been associated with structural brain abnormalities, synaptic deficits, and altered neuronal connectivity, which are common features in neuropsychiatric disorders. The multifaceted roles of DISC1 in cellular processes and its potential as a biomarker or therapeutic target underscore its significance in neuroscience and psychiatry research.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Disrupted In Schizophrenia 1 Protein (DISC1)


host

Rabbit


conjugation

Biotin


form

Liquid


tested applications

ELISA


purity

> 95%


purification

Purified by Protein G.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.


or code

DISC1


dry ice

No


availability

Shipped within 5-10 working days.


alias

DISC1, C1orf136, SCZD9, disrupted in schizophrenia 1, DISC1 scaffold protein


NCBI accession

NM_018662.2


note

This product is for research use only.


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