Dipeptidyl Peptidase 4 (DPP4) Antibody

Este producto es parte de DPP4 - dipeptidyl peptidase 4
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286€ (50 µg)

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935106861
info@markelab.com
name
Dipeptidyl Peptidase 4 (DPP4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421274
tested applications
FCM

Description

Dipeptidyl Peptidase 4 (DPP4) Antibody is a Mouse Monoclonal antibody for the detection of Dipeptidyl Peptidase 4 (DPP4) in Human samples.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Dipeptidyl Peptidase 4 (DPP4)
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2b Kappa
Clone ID
P733
Purity
> 95%
Purification
Purified by Protein A/G affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
FCM
Buffer
0.01 M PBS, pH 7.4.
Availability
Shipped within 5-12 working days.
Storage
Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.
Dry Ice
No
UniProt ID
P27487
Gene ID
1803
NCBI Accession
NP_001926.2
Alias
CD26,ADABP,ADCP2,DPPIV,TP103,Dipeptidyl peptidase 4,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,T-cell activation antigen CD26
Background
Antibody anti-DPP4
Status
RUO
Note
Concentration: 1 mg/ml - 

Descripción

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Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor(TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix(ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhesion, migration and tube formation. When overexpressed, enhanced cell proliferation, a process inhibited by GPC3. Acts also as a serine exopeptidase with a dipeptidyl peptidase activity that regulates various physiological processes by cleaving peptides in the circulation, including many chemokines, mitogenic growth factors, neuropeptides and peptide hormones. Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline.

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