Dipeptidyl Peptidase 4 / CD26 (DPP4) Antibody
507€ (250 µg)
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Name
Dipeptidyl Peptidase 4 / CD26 (DPP4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx414070
Tested Applications
ELISA, FCM
Description
Dipeptidyl Peptidase 4 (CD26) Antibody is a Rat Monoclonal antibody against Dipeptidyl Peptidase 4 (CD26).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Dipeptidyl Peptidase 4 / CD26 (DPP4) |
| Host | Rat |
| Reactivity | Mouse |
| Assay Type | Concentration: 1.0 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a |
| Purification | Purified |
| Size 1 | 250 µg |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | PBS. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P28843 |
| Gene ID | 13482 |
| Alias | CD26,ADABP,ADCP2,DPPIV,TP103,Dipeptidyl peptidase 4,Adenosine deaminase complexing protein 2,ADCP-2,Dipeptidyl peptidase IV,T-cell activation antigen CD26 |
| Background | Antibody anti-DPP4 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Dipeptidyl peptidase 4 (DPP4), also known as CD26, is a transmembrane glycoprotein and serine protease that plays a significant role in regulating glucose metabolism, immune function, and cell signaling. It is expressed on the surface of various cell types, including epithelial cells, endothelial cells, and immune cells such as T cells and B cells. DPP4 is widely known for its role in glucose homeostasis through its enzymatic activity, where it deactivates incretin hormones like glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These hormones promote insulin release in response to meals, and their inactivation by DPP4 reduces insulin secretion, thereby impacting blood sugar levels. Beyond its metabolic functions, DPP4 also participates in various immune regulatory pathways. As CD26, it is involved in T-cell activation and co-stimulation. DPP4 is linked to inflammatory processes and certain cancers, particularly due to its enzymatic activity and role in regulating immune responses. Additionally, the soluble form of DPP4 (sDPP4), which circulates in the plasma, plays a role in systemic metabolic and immune regulation.
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