Diacylglycerol Kinase Theta (DGKQ) Antibody
312€ (60 µl)
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935106861
info@markelab.com
name
Diacylglycerol Kinase Theta (DGKQ) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx002775
tested applications
WB
Description
DGKQ Antibody is a Rabbit Polyclonal antibody against DGKQ. The protein encoded by this gene contains three cysteine-rich domains, a proline-rich region, and a pleckstrin homology domain with an overlapping Ras-associating domain. It is localized in the speckle domains of the nucleus, and mediates the regeneration of phosphatidylinositol (PI) from diacylglycerol in the PI-cycle during cell signal transduction.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Diacylglycerol Kinase Theta (DGKQ) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | WB: 1/200 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 60 µl |
| Size 2 | 120 µl |
| Size 3 | 200 µl |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P52824 |
| Gene ID | 1609 |
| NCBI Accession | NP_001338.2 |
| Background | Antibody anti-DGKQ |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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DGKQ antibody
Phosphorylates diacylglycerol(DAG) to generate phosphatidic acid(PA). May regulate the activity of protein kinase C by controlling the balance between these two signaling lipids. Activated in the nucleus in response to alpha-thrombin and nerve growth factor(By similarity). May be involved in cAMP-induced activation of NR5A1 and subsequent steroidogenic gene transcription by delivering PA as ligand for NR5A1. Acts synergistically with NR5A1 on CYP17 transcriptional activity.
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