Diablo IAP-Binding Mitochondrial Protein (DIABLO) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Diablo IAP-Binding Mitochondrial Protein (DIABLO) Antibody is a Rabbit polyclonal antibody for the detection of Human Diablo IAP-Binding Mitochondrial Protein (DIABLO).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Diablo IAP-Binding Mitochondrial Protein (DIABLO) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NR28 |
| Gene ID | 56616 |
| NCBI Accession | NP_001265231.1 |
| Background | Antibody anti-DIABLO |
| Status | RUO |
Descripción
Related Products
DIABLO antibody
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins(IAP). Inhibits the activity of BIRC6/bruce by inhibiting its binding to caspases. Isoform 3 attenuates the stability and apoptosis-inhibiting activity of XIAP/BIRC4 by promoting XIAP/BIRC4 ubiquitination and degradation through the ubiquitin-proteasome pathway. Isoform 3 also disrupts XIAP/BIRC4 interacting with processed caspase-9 and promotes caspase-3 activation. Isoform 1 is defective in the capacity to down-regulate the XIAP/BIRC4 abundance.This antibody recognizes all the three isoforms of DIABLO.
Ver Producto
Recombinant Human DIABLO
Ver Producto