Desmoglein 1/3 (DSG1/3) Antibody

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312€ (50 µg)

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935106861
info@markelab.com
name
Desmoglein 1/3 (DSG1/3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx421782
tested applications
ELISA, FCM

Description

Desmoglein 1/3 (DSG1/3) Antibody is a Mouse Monoclonal antibody for the detection of Desmoglein 1/3 (DSG1/3) in Human samples.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Desmoglein 1/3 (DSG1/3)
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Clone ID
F019
Purity
> 95% (SDS-PAGE)
Purification
Purified by Protein A/G affinity chromatography.
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, FCM
Buffer
0.01 M PBS, pH 7.4, 0.09% Sodium azide.
Availability
Shipped within 5-12 working days.
Storage
Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles.
Dry Ice
No
UniProt ID
Q02413, P32926
Background
Antibody anti-DSG1
Status
RUO
Note
Concentration: 1 mg/ml -

Descripción

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This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

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