Desmoglein 1/3 (DSG1/3) Antibody

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Description
Desmoglein 1/3 (DSG1/3) Antibody is a Mouse Monoclonal antibody for the detection of Desmoglein 1/3 (DSG1/3) in Human samples.
Documents del producto
Product specifications
Category | Primary Antibodies |
Immunogen Target | Desmoglein 1/3 (DSG1/3) |
Host | Mouse |
Reactivity | Human |
Clonality | Monoclonal |
Conjugation | Unconjugated |
Isotype | IgG2a |
Clone ID | F019 |
Purity | > 95% (SDS-PAGE) |
Purification | Purified by Protein A/G affinity chromatography. |
Size 1 | 50 µg |
Size 2 | 100 µg |
Form | Liquid |
Tested Applications | ELISA, FCM |
Buffer | 0.01 M PBS, pH 7.4, 0.09% Sodium azide. |
Availability | Shipped within 5-12 working days. |
Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. |
Dry Ice | No |
UniProt ID | Q02413, P32926 |
Background | Antibody anti-DSG1 |
Status | RUO |
Note | Concentration: 1 mg/ml - |
Descripción
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This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.
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