Desmoglein 1 (DSG1) Peptide

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175.5€ (100 µg)

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935106861
info@markelab.com
name
Desmoglein 1 (DSG1) Peptide
category
Proteins and Peptides
provider
Abbexa
reference
abx616015
tested applications
P-ELISA

Description

Desmoglein 1 (DSG1) Peptide is a synthetic peptide.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Desmoglein 1 (DSG1)
Host
Synthetic
Recommended Dilution
BL (predicted): 0.5 mg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation
Unconjugated
Observed MW
Sequence Fragment: Internal region: C-YTTSDTLKPSVHVHD
Size 1
100 µg
Form
Lyophilized Reconstitute in deionized water.
Tested Applications
P-ELISA
Buffer
Prior to lyophilization: Deionized water.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
1828
NCBI Accession
NP_001933.2
Background
Protein DSG1
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

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