Desmoglein-1 (DSG1) Antibody

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260€ (50 µg)

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935106861
info@markelab.com
name
Desmoglein-1 (DSG1) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx455805
tested applications
ELISA, WB, IHC

Description

Desmoglein-1 (DSG1) Antibody is a Rabbit polyclonal antibody for the detection of Human Desmoglein-1 (DSG1).

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Primary Antibodies
Immunogen Target
Desmoglein-1 (DSG1)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
50 µg
Size 2
100 µg
Form
Liquid
Tested Applications
ELISA, WB, IHC
Buffer
0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300.
Availability
Shipped within 5-12 working days.
Storage
Store at 4 °C if the entire vial will be used within 1-2 weeks. For long-term storage, aliquot and store at -20 °C or -80 °C. Avoid repeated freeze-thaw cycles.
Dry Ice
No
UniProt ID
Q02413
Gene ID
1828
NCBI Accession
NP_001933.2
Background
Antibody anti-DSG1
Status
RUO
Note
Concentration: 1.91 mg/ml -

Descripción

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This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

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