Dengue Virus Type 3 Genome Polyprotein Antibody
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Description
Dengue Virus Type 3 Genome Polyprotein Antibody is a Rabbit polyclonal antibody for the detection of Dengue virus type 3 (strain Philippines/H87/1956) Genome Polyprotein.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Genome Polyprotein |
| Host | Rabbit |
| Reactivity | Virus |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P27915 |
| Background | Antibody anti-DENGUE |
| Status | RUO |
Descripción
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Genome Polyprotein Antibody is a Rabbit Polyclonal antibody against Genome Polyprotein found in the Dengue virus. The genome polyprotein is cleaved into several chains. Capsid protein C self-assembles to form an icosahedral capsid about 30 nm in diameter. The capsid encapsulates the genomic RNA. prM acts as a chaperone for envelope protein E during intracellular virion assembly by masking and inactivating envelope protein E fusion peptide. prM is matured in the last step of virion assembly, presumably to avoid catastrophic activation of the viral fusion peptide induced by the acidic pH of the trans-Golgi network. After cleavage by host furin, the pr peptide is released in the extracellular medium and small envelope protein M and envelope protein E homodimers are dissociated.
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