Delta-Like Protein 4 (DLL4) Antibody
383.5€ (100 µl)
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935106861
info@markelab.com
name
Delta-Like Protein 4 (DLL4) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx012164
tested applications
ELISA, FCM
Description
This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Delta-Like Protein 4 (DLL4) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1/10000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2b |
| Purification | Purified from ascites by Protein G chromatography. |
| Size 1 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, FCM |
| Buffer | PBS, containing 0.05% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9NR61 |
| Gene ID | 54567 |
| OMIM | 605185 |
| Background | Antibody anti-DLL4 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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Human DLL4 (Delta-like protein 4) ELISA Kit
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DLL4 antibody
Involved in the Notch signaling pathway as Notch ligand(PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting(PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types(By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate(PubMed:17728344).
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