Cytosolic Non-Specific Dipeptidase (CNDP2) Antibody
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Description
Cytosolic Non-Specific Dipeptidase (CNDP2) Antibody is a Rabbit polyclonal antibody for the detection of Human Cytosolic Non-Specific Dipeptidase (CNDP2).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytosolic Non-Specific Dipeptidase (CNDP2) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q96KP4 |
| Gene ID | 55748 |
| NCBI Accession | NP_001161971.1 |
| Background | Antibody anti-CNDP2 |
| Status | RUO |
Descripción
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Human CNDP2 (Cytosolic non-specific dipeptidase) ELISA Kit
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CNDP2 antibody
Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly(PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase(MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation(PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma(HCC) cells(PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis(PubMed:25964343).
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