Cytochrome P450 3A4 (CYP3A4) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Cytochrome P450 3A4 (CYP3A4) Antibody is a Recombinant Rabbit Monoclonal antibody for the detection of Human CYP3A4.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cytochrome P450 3A4 (CYP3A4) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Expression | Recombinant |
| Purification | Purified by affinity chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, 150 mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08684 |
| Gene ID | 1576 |
| OMIM | 124010 |
| Background | Antibody anti-CYP3A4 |
| Status | RUO |
Descripción
Related Products
Human CYP3A4(Cytochrome P450 3A4) ELISA Kit
Ver Producto
anti- CYP3A4 antibody
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified.
Ver Producto